MAD ® Muscosal, Atomization, Devices. Rapid Medication Delivery width targeted fine mist


MAD Nasal-Mucosal Atomization Device delivers intranasal medication in a fine mist which enhances absorption and improves bioavailability for fast and effective drug delivery. By eliminating the need to establish an IV, delivery is rapid which is useful for treating various emergency, ENT, anesthesia and pediatric conditions.

MAD Nasal Features and Benefits

Safe and Painless

  • No needle - No shot - No pain
  • No risk of needlestick
  • Less frightening for children
  • Disposable

Rapidly Effective

  • Atomized nasal medications absorb directly into the blood stream, avoiding first pass metabolism
  • Atomized medications absorb directly into the brains and CSF via
    the olfactory mucosa (nose-brain pathway)
  • Achieves serum medication levels comparable to injections

Controlled administration

  • Exact dosing, exact volume
  • Titratable to effect (repeat if needed)
  • Atomizes in any position
  • Atomized particles are optimal size for deposition across broad area of mucosa

Minimal Resource Utilization

  • Nasal drug administration is quick and easy
  • No sterile technique is required
  • Eliminates IV set-up time

Benefits Comparison to Alternate Delivery Methods

Product Specfications

Typical particle size:
30-100 microns
System dead space:
0.13 mL MAD100 and MAD140 / 0.07 mL MAD300
Tip diameter:
0.17 inches (4.3 mm)
Applicator length:
1.65 inches (4.2 cm)

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Step 1

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Step 8

Step 10

Materials

Step 1

One each MAD Nasal device with vial adapter and 3 mL syringe (Cat. #MAD140)

Step 2 - Medication of appropriate concentration for intranasal medication delivery
• High concentration - Low Volume

Procedure

Step 3 - Remove and discard the green vial adapter cap.

Step 4 - Pierce the medication vial with syringe vial adapter.

Step 5 - Aspirate the proper volume of medication required to treat the patient (an extra 0.1 mL of medication should be drawn up to account for the dead space in the device).

Step 6 - Remove (twist off) the syringe from the vial adapter.

Step 7 - Attach the MAD device to the syringe via the luer-lock connector.

Step 8 - Using the free hand to hold the crown of the head stable, place the tip of the MAD snugly against the nostril aiming slightly up and outward (toward the top of the ear).

Step 9 - Briskly compress the syringe plunger to deliver half of the medication into the nostril.

Step 10 - Move the device over to the opposite nostril and administer the remaining medication into that nostril.

Key Concepts

Minimize volume, maximize concentration

• 1/3 mL per nostril is ideal, 1 mL is maximum
• Use the appropriately concentrated drug

Maximize total mucosal absorptive surface area

• Atomize the drug (rather than drip it in) to cover braod surface area
• Use BOTH nostrils to double the absorptive surface area
• Aim slightly up and outwards to cover the turbinates and olfactory mucosa

Beware of abnormal mucosal characteristics

• Mucous, blood and vasoconstrictors reduce absorption
• Suction nostrils or consider alternate drug delivery method in these situations

Download Intranasal Medication Delivery Procedure using the MAD Nasal

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Catalog Number
MAD Nasal Product Description
QTY/CaseQTY/Box
MAD100 MAD Nasal Drug Delivery Device w/3mL Syringe 100/case 25/box
MAD110 MAD Nasal Drug Delivery Device w/1mL Syringe 100/case 25/box
MAD130 MAD Nasal Drug Delivery Device w/1mL Syringe and Vial Adapter 100/case 25/box
MAD140 MAD Nasal Drug Delivery Device w/3mL Syringe and Vial Adapter 100/case 25/box
MAD300 MAD Nasal Drug Delivery Device w/o 3mL Syringe 100/case 25/box

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